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FDA Approves Diet Drug Qsymia. Qsymia, developed by California-based Vivus Inc., combines two already prescribed medications -- the stimulant phentermine and the anti-seizure drug Topamax (topiramate) -- in a controlled-release pill that is taken once a day. Association of Pharmacological Treatments for Obesity With Weight Loss and. orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and. Drug Administration (FDA) has approved 5 weight loss drugs (orlistat,
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